First-in-class drug discovery

Novel Targets in the Nuclear Receptor Family

Orphagen discovers and develops small molecules at drug targets that have significant unrealized potential in areas of high clinical need. We focus on the unexplored or “orphan” members of the nuclear receptor family, the source of many successful drugs.

Orphagen has been primarily supported by non-dilutive funding, from grants, contracts and partnership milestones.

orphagen pharmaceuticals


Orphagen Team

Our scientists and management team are committed to the best we can bring to bear in pursuit of new therapies. We are drug hunters. .



Our mission is translational drug discovery and development with novel targets leading to first-in-class industry partnerships. .